BioCosm
Registry code: 011645fbf6c23a7c
Explore thousands of biotech drugs, diagnostics, gene targets, and pipeline compounds. Nodes carry structured metadata; many also have full analytical writeups (summary, mechanism, trial design, probability-of-success estimate, risks, assessment) with citations, and link to targets, companies, revenue, and trial outcomes. Start with search_nodes, then get_node / get_writeup; find_by_phase, find_by_target, and get_company_portfolio handle portfolio queries; get_coverage reports what data is and isn't populated.
IMPORTANT - read before relying on anything: BioCosm is an AI-powered, automatically…
- endpoint
- https://biocosm-mcp.fly.dev/mcp
- protocol
- http-sse ·2025-06-18
- authentication
- none observed
- public key
- none — nobody has proven they own this listing · is it yours? claim it
- karma
- 0 · newcomer
- Is BioCosm live?
- Yes — it answered the hub's last check (checked 1h ago). It answered 98% of checks over the last 30 days.
- Is BioCosm free to use?
- Yes — the hub reached it with no key and no payment.
- What tools does BioCosm have?
- 13 tools: get_writeup, get_node, find_by_target, search_nodes, get_company_portfolio, find_by_phase, get_node_freshness, get_pos_score, ….
- Is BioCosm safe to connect?
- The hub found no text in its card or tool descriptions aimed at the agent reading them. It measures what the server answers, not its code — grant it only the access its tools need.
90 days 97.6%· all time 97.6%
last good check
of 13 tools
- degraded → live
- live → degraded· timeout after 20000ms
- degraded → live
- live → degraded· timeout after 20000ms
- degraded → live
- used for
- search biotech drugs
- find drugs by gene target
- get probability of success
- get company pipeline
- takes → gives
- text → data
- tools
- 13 reads
Calls placed through this hub's router, from its own receipts. Every caller and every payer counts the same; the chain total is counted from three payers.
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what callers paid
Price is per tool, not per server. An agent whose handshake is open can hold tools that demand a key or a payment, and one figure for the whole agent sends callers into a wall.
get_coverage reads open 5h ago
Report BioCosm's actual data coverage so you never mistake missing data for a real-world zero. An empty or absent field on a node means "not in BioCosm's data," never a true zero. BioCosm is AI-generated and may contain errors.
{ "type": "object", "properties": {}, "additionalProperties": false }arguments 5 linesget_stats reads open 15h ago
Get a high-level overview of the BioCosm database: total nodes, writeups, companies, breakdowns by type/status/domain, validation scores, and recent pipeline runs.
{ "type": "object", "properties": {}, "additionalProperties": false }arguments 5 linesget_staleness_report reads open 15h ago
Get writeup staleness report: overall stats, top stale nodes, data source freshness.
{ "type": "object", "properties": { "limit": { "type": "integer", "default": 20, "description": "Number of top stale nodes to return (default 20)" } }, "additionalProperties": false }arguments 11 linesget_writeup reads unknown never probed
Get the full writeup for a BioCosm node, including all sections, citations, structured data, and validation score.
{ "type": "object", "required": [ "node_id" ], "properties": { "node_id": { "type": "string", "description": "The node identifier (e.g. \"pembrolizumab\")" } }, "additionalProperties": false }arguments 13 linesget_node reads unknown 8h ago
Get full details for a single BioCosm node: identity and all name aliases, classification, gene targets and mechanism, therapeutic areas, companies, revenue history where available (sparse: ~100 drugs, mostly blockbusters, as annualized quarterly estimates; source links when present), probability-of- success predictions for pipeline drugs (with confidence intervals and contributing factors), structured clinical trial outcomes, external cross-references, and writeup availability. Empty fields mean "not in BioCosm's coverage," NOT zero or absent in reality.
{ "type": "object", "required": [ "node_id" ], "properties": { "node_id": { "type": "string", "description": "The node identifier (e.g. \"pembrolizumab\", \"trastuzumab\")" } }, "additionalProperties": false }arguments 13 linesfind_by_target reads unknown 8h ago
Find all drugs that target a specific gene/protein.
{ "type": "object", "required": [ "target_gene" ], "properties": { "limit": { "type": "integer", "default": 50, "description": "Maximum results (default 50, max 200)" }, "target_gene": { "type": "string", "description": "Gene symbol or target name (e.g. \"EGFR\", \"KRAS\", \"PD-1\")" } }, "additionalProperties": false }arguments 18 linessearch_nodes reads unknown 11h ago
Search BioCosm nodes by name, gene symbol, target, therapeutic area, or company. Results are ranked: exact name/brand matches first, then partial name matches, with a node-type prior (canonical drug/diagnostic nodes rank above gene-target nodes, which rank above ChEMBL salt-form duplicates). Nodes matched only via description/company/area rank last. Each result includes a `name` field for disambiguation.
{ "type": "object", "required": [ "query" ], "properties": { "limit": { "type": "integer", "default": 20, "description": "Maximum results to return (default 20, max 100)" }, "query": { "type": "string", "description": "Search term (e.g. \"breast cancer\", \"pembrolizumab\", \"Merck\")" } }, "additionalProperties": false }arguments 18 linesget_company_portfolio reads unknown 11h ago
Get a company's full drug/diagnostic portfolio from BioCosm.
{ "type": "object", "required": [ "company_name" ], "properties": { "company_name": { "type": "string", "description": "Company name (e.g. \"Merck\", \"Roche\", \"Illumina\")" } }, "additionalProperties": false }arguments 13 linesfind_by_phase reads unknown 15h ago
List drugs/diagnostics at a specific clinical phase.
{ "type": "object", "required": [ "phase" ], "properties": { "limit": { "type": "integer", "default": 100, "description": "Maximum results (default 100, max 500)" }, "phase": { "type": "string", "description": "One of \"approved\", \"on_market\", \"phase3\", \"phase2\", \"phase1\",\n \"in_development\", \"cleared\", \"ldt\", \"ruo\"" }, "node_type": { "anyOf": [ { "type": "string" }, { "type": "null" } ], "default": null, "description": "Optional filter — \"drug\", \"pipeline\", \"diagnostic\", \"target\"" } }, "additionalProperties": false }arguments 30 linesget_node_freshness reads unknown 8h ago
Get freshness details for a single node: writeup age, enrichment hash match, staleness score, validation score.
{ "type": "object", "required": [ "node_id" ], "properties": { "node_id": { "type": "string", "description": "The node identifier (e.g. \"pembrolizumab\")" } }, "additionalProperties": false }arguments 13 linesget_pos_score reads unknown 5h ago
Get the Probability of Success estimate for a node, including the base rate, adjustment factors with reasoning, confidence interval, and model version. Returns None for nodes without a PoS score (typically only late-stage pipeline drugs are scored).
{ "type": "object", "required": [ "node_id" ], "properties": { "node_id": { "type": "string", "description": "Node identifier" } }, "additionalProperties": false }arguments 13 lineslist_by_therapeutic_area reads unknown 5h ago
List all nodes in a given therapeutic area.
{ "type": "object", "required": [ "area" ], "properties": { "area": { "type": "string", "description": "Therapeutic area to search (e.g. \"breast cancer\", \"non-small cell lung cancer\")" }, "limit": { "type": "integer", "default": 50, "description": "Maximum results (default 50)" } }, "additionalProperties": false }arguments 18 linesfind_related reads unknown 11h ago
Find nodes connected to a given node. Three relationship types are derived on-the-fly: - "drug_target": for a drug, the targets it hits (and vice versa for a target node, the drugs that hit it) - "same_company": drugs sharing a company with this node - "same_target_class": drugs with the same mechanism_class
{ "type": "object", "required": [ "node_id" ], "properties": { "limit": { "type": "integer", "default": 30, "description": "Maximum results per link type (default 30)" }, "node_id": { "type": "string", "description": "Source node identifier" }, "link_type": { "anyOf": [ { "type": "string" }, { "type": "null" } ], "default": null, "description": "Optional filter — one of \"drug_target\", \"same_target_class\",\n \"same_company\". If None, returns all three groups." } }, "additionalProperties": false }arguments 30 lines
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